Karachi, being the largest city in Pakistan, has several district and session courts to handle legal matters and provide judicial services to its residents. The district and session courts in Karachi are organized hierarchically, with different courts having jurisdiction over specific types of cases. Here are some of the important district and session courts in Karachi:

1. District and Sessions Court South: Located in the southern part of Karachi, this court deals with civil and criminal cases falling within its jurisdiction.
2. District and Sessions Court East: Situated in the eastern part of Karachi, this court handles civil and criminal cases falling within its jurisdiction.
3. District and Sessions Court Malir: This court is located in the Malir area of Karachi and has jurisdiction over civil and criminal cases in that region.
4. District and Sessions Court West: Situated in the western part of Karachi, this court deals with civil and criminal cases falling within its jurisdiction.
5. District and Sessions Court Central: Located in the central area of Karachi, this court handles civil and criminal cases within its jurisdiction.

In addition to these district and sessions courts, there are also specialized courts in Karachi, such as family courts, anti-terrorism courts, banking courts, and others, which deal with specific types of cases. These courts are established to ensure efficient and effective dispensation of justice in their respective areas of expertise.

Please note that the information provided above is based on the knowledge available up until September 2021, and there may have been changes or additions to the court system in Karachi since then. It is always recommended to consult the official sources or legal authorities for the most up-to-date and accurate information regarding the district and session courts in Karachi.